Deb Smith, age fifty-six, came to her nurse practitioner (NP)with fatigue, pallor, dyspnea on exertion, and palpitations. Her laboratory report indicates that her hematocrit, hemoglobin, and reticulocyte counts are low; that her MCV is high; and that her MCH and MCHC are normal. Her diagnosis is pernicious anemia. Answer the following questions regarding Deb’s anemia and provide the pathophysiology associated with the body’s response to this disease process.. Why should Deb’s NP ask her about paresthesia and ataxia? .Why did her NP prescribe vitamin B12 by intramuscular injection rather than orally? .What causes pernicious anemia? .What are the technical terms that describe an anemia with high MCV and normal MCH?
While the processes that you discussed will eventually cause symptoms of 1312 deficiencies many individuals will have delayed onset of the deficiency and the onset of symptoms for a period of five to ten years. What is the cause of the delay between onset of the deficiency and the symptoms?