Clinical problem

    1.Reason for choosing this topic 2.The PICOT question which is (Are males 50 years of age and older (P- Patient Population) who have a history of smoking all their lives (I- Area of Interest) at an increased risk of developing esophageal cancer compared with males age 50 and older (C- Comparison) who have no smoking (O-Outcome) history during the period of their 5years (T- Time)) 3.Possible integration of the evidenced that you found in clinical practice 4. Methods to evaluate the effectiveness of implementation P: Patient Population I: Intervention or area on Interest C: Comparison intervention or group O: Outcome T: Time