Pharmacotherapy for Cardiovascular Disorders

Patient AO has a history of obesity and has recently gained 9 pounds. The patient has been diagnosed with hypertension and hyperlipidemia. Drugs currently prescribed include the following: • Atenolol 12.5 mg daily • Doxazosin 8 mg daily • Hydralazine 10 mg qid • Sertraline 25 mg daily • Simvastatin 80 mg daily 1 Write an explanation of how age might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study 2 Describe how changes in the processes might impact the patient’s recommended drug therapy. 3 Explain how you might improve the patient’s drug therapy plan.

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