Renal dosage adjustments based on est CrCI as calculated by Cockcrolligault equation, vs estGFR as calculated by IvIDRD

Renal dosage adjustments based on est CrCI as calculated by CockcrofUgault equation, vs estGFR as calculated by MDRD? There are some merits to each one, especially since there are unknowns that need to be corrected for with each (which weight to use, how do you assign IBW for pts < 60in, how to account for changes in renal
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