produce a concise review of the role of infection in acute exacerbations of chronic obstructive pulmonary disease (COPD). In this review, you should briefly explain what COPD is, the magnitude of the problem (prevalence, morbidity and mortaility), what constitutes an acute exacerbation before then expanding on the role of infection in these exacerbations. You should also briefly describe the role for antimicrobial therapy in managing infection associated acute exacerbations.
