SNP rs1051730 and predisposition to COPD/lung cnacer and a link to smoking behaviour
It is a scientific writing, and 4 areas need to be covered:
1. In introduction: the nature of the genetic change (the SNP), factors that cause it, prevelnce and geographical distribtion (if possible).
2. the identification method for the SNP, mentioning two current methods (one of them is Illumina) and their preincples, and if there is benefits/restrictions to the methods.
3. The affect of the SNP on the cell function, mainly the affects on gene product function , and its affects on cellular mechanisms and pathway.
4. For this part answer the following questions for the diseases in the title and smoking behaviour. (Does this change result in a disease? Does it increase the likelyhood of getting a disease? Alter the severity of disease? How does the change contribute to the cause of the associated disease)